One target
- Mortal Strike while Colossal Might is below 10 stacks.
- Rend (through Cleave when you have it) when it's about to run out, or before Colossus Smash with 10 seconds or less left.
- Ravager right before Colossus Smash, then Avatar, Colossus Smash and Champion's Spear.
- Demolish inside Colossus Smash while Colossal Might is up.
- Heroic Strike, Execute with two Sudden Death charges, Mortal Strike.
- Execute, Overpower, then Slam as the filler and Wrecking Throw last.